Know when to get help.

A severe allergic reaction calls for emergency help.

Swelling in your face or tongue, or trouble breathing, can point to a severe allergic reaction that needs emergency care.

Seek emergency care right away for these severe symptoms.

Act on severe belly pain that does not ease.

The Wegovy (semaglutide) label warns about swelling and irritation in a body organ called the pancreas.

A sign of this problem is severe belly pain or pain that does not go away.

The pain may spread to your back.

Ask a health professional to assess that pain promptly.

Report heavy vomiting or diarrhea.

Severe stomach symptoms can cause fluid loss and kidney injury; the label reports cases that needed kidney treatment.

The label calls for kidney checks when symptoms could cause major fluid loss.

Ask the person treating you what to do if these symptoms are severe or keep going.

Discuss common symptoms, too.

Nausea, meaning feeling sick to your stomach, diarrhea, vomiting and constipation were common in Wegovy injection trials.

Ask how to contact your treating professional and when to arrange a check-in before the next routine visit.

Ask about these illnesses in your health records.

The label forbids semaglutide use if you or your family have a history of medullary thyroid cancer, which is rare.

People with MEN 2 also cannot use semaglutide under the label; this rare illness can be inherited from a parent.

This warning names MEN 2 specifically. If you do not recognise that name, ask the health professional to check your family’s medical history with you.

A past serious allergic reaction to semaglutide or any other product ingredient also rules out its use under the label.

Keep the thyroid finding in context.

Semaglutide labels have their strongest warning, called a boxed warning, covering thyroid tumors observed in mice and rats.

It is unknown whether people develop these thyroid tumors from semaglutide.

Mention pregnancy plans and planned procedures.

Pregnancy planning and procedures involving deep sedation or anesthesia are part of the label’s cautions.

Deep sedation or anesthesia means medicine that makes you very sleepy or unconscious for a procedure. Ask the person prescribing your medicine and the procedure team to plan together.